Elizabeth HolmesPalo Alto, California based Elizabeth Holmes quit Stanford University and made a $4.5 billion fortune as a health technology entrepreneur. Theranos, the company she founded in 2003 to “shape the future of lab testing” turned her into a self-made billionaire by the age of 30 and with elder statesmen including Henry Kissinger and George Shultz on her board, her sphere of influence is plainly great. Surprisingly, Holmes was described as “the female Mark Zuckerberg that Silicon Valley has been waiting for” in 2014 but is surprisingly afraid of needles.

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